Primary Cells & Culture Media

Organoid and spheroid cultures as well as co-culture systems represent advanced three-dimensional models that mimic the complexity of tissues and organs in vitro.These approaches result in more complex and physiologically relevant systems compared to traditional monolayer cultures, allowing researchers to study cellular interactions, tissue development, disease mechanisms, and drug responses within a setting that closely mimics in vivo conditions.

Three-dimensional, multilineage human skin models—an area where CellSystems® has historically acquired extensive experience—serve as a basis for the reproduction and study of various skin diseases, as well as their treatment in vitro. Furthermore, these models have significantly advanced research in critical areas such as wound healing, and burn therapy. Additionally, the emergence of Organ-on-a-Chip Technology has provided captivating insights into the complex microenvironment and physiological responses of human organs in vitro. In a recent publication, primary cells, culture media, and extracellular matrix proteins were utilized in a microfluidic two-channel co-culture to shed light on the dynamics of the vaginal microbiome for understanding female reproductive tract health and disease.

For a comprehensive overview about our extracellular matrices, adhesion molecules and bioprinting materials, visit Matrix Proteins & Bioprinting.