Available Now: Normal Human Cardiac Microvascular Endothelial Cells

Normal Human Cardiac Microvascular Endothelial Cells (#FC-0053), are isolated from human heart tissue, expanded three times, and cryopreserved at the earliest passage to ensure maximum viability, purity, and plating efficiency.
When cultured in VascuLife® VEGF-Mv Microvascular Endothelial Growth Medium Complete Kit (#LL-0005), these human primary cells provide an excellent low-serum model for studying angiogenesis, atherosclerosis, and vascular biology.
The Human Cardiac Microvascular Endothelial Cells are cultured without antimicrobials or phenol red in VascuLife® Media. For convenience, a vial of Gentamicin and Amphotericin B (GA; #LS-1104) is included with the VascuLife® VEGF-Mv Microvascular Endothelial Growth Medium Complete Kit (#LL-0005), to prevent fungal or bacterial contamination of eukaryotic cell cultures. Phenol red (#LS-1009) is also available separately, although not necessary for cell proliferation.

Spotlight on Understanding Vaginal Microbiome Dynamics with Organ Chips

Dysbiotic Vaginal Complications: Insights from Human Vagina and Cervix Chips Co-culture

Researchers used Organ-on-a-Chip technology to investigate the impact of cervicovaginal mucus on dysbiotic vaginal conditions. The study, detailed in “Modulation of dysbiotic vaginal complications by cervical mucus revealed in linked human vagina and cervix chips by Gutzeit et al. (bioRxiv, 2023) doi: https://doi.org/10.1101/2023.11.22.568273, highlights dysbiotic changes in the female genital microbiome and their links to various health issues. The study employed a microfluidic two-channel co-culture of a cervix chip and a vagina chip, revealing that cervical mucus collected from the cervix chip protected the vaginal epithelium on the vagina chip from inflammation and epithelial cell injury. Proteomic analysis identified potential diagnostic biomarkers or therapeutic targets for bacterial vaginosis. The research underscores the utility of organ chip technology in understanding female reproductive tract health and disease.

Notably, the wide range of cells, media, and coating reagents required for establishing the Organ Chips are available in Europe through CellSystems®:

Female Reproductive Cells

Extracellular Matrices

Adhesion Peptides


MEET US at the 50. ADF

CellSystems® will be participating in this year’s 50. Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung e. V., ADF

  • Date: March 06-09, 2024
  • Booth Number: U11
  • Location: Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf, Germany

Explore our latest products & services. We look forward to engaging with you at ADF and providing insights into our innovative solutions for dermatology research.

See you at our booth!



Update – available hematopoietic cells

We significantly broadened the portfolio of human Mononuclear Cells (MNCs) and isolated hematopoietic cell types from

  • Leukapheresed Peripheral Blood (Leukapheresed PB)
  • Normal Peripheral Blood (Normal PB)
  • Mobilized Peripheral Blood (Mobilized PB)
  • Cord Blood
  • Bone Marrow and
  • Plasma.

We now offer specific subsets of T cells, B cells, NK cells and monocytes isolated by positive selection of target cells or by depletion of non-target cells. Furthermore, CD34+ Hematopoietic Stem Cells as well as the CD34 cells (cell fraction depleted of CD34+ cells) are available from several sources, also as “matched sets” from the same donor.

Furthermore, we also offer a wide variety of cells differentiated from induced Pluripotent Stem Cells (iPSCs). The ready-to-use hematopoietic iPSC-derived cells come with optimized medium for most reliable results.

Have a look on the table about available Hematopoietic Celltypes and Sources.

Click on the following links for a complete list of available human Primary Cells as well as ready-to-use iPSC-derived cells.




26 Assays Using PureCol Collagen

Collagen is the most abundant protein in the body and is thus the most widely used ECM protein in research across hundreds of various assays.

PureCol® Type I Collagen is the most popular collagen product, being 3 mg/ml of type I atelocollagen (>99.9% pure), and is the product referenced in each of the assays below. Other ABM Collagen products may be substituted in these assays if different mechanical properties of the collagen are desired (ie. use Telocollagen for stiffer hydrogels to evaluate changes in migration related to stiffness). Descriptions of some of the assays are found below the chart.

Assay Title Reference
Boyden Chamber https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926928/
Spheroid Invasion https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926928/
Single Cell Motility https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926928/
Cell Viability https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991007/
Aortic Ring https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907187/
3D Chemotaxis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836243/
Cell Line Generation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812522/
Collagen Migration https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751638/
Cell Proliferation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858314/
Air-Liquid Interface https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651658/
Gel Contraction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556235/
3D Migration https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523719/
Tumor-On-Chip 3D Motility https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534269/
In Vitro Granuloma Models https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486295/
Injectable Gels https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438067/
3D Cytotoxicity co-culture https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410835/
Invasion https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383389/
CRT (Calreticulin) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436107/
Cell Binding https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195475/
Melanoma Spheroid Invasion https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115293/
Stiffness https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428240/
LH Enzymatic Activity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055892/
In Vitro 3D Cyst https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251518/
Scratch/Wound Healing https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830896/
Tube Formation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830896/
Permeability https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873778/

(published 01/26/23: Advanced BioMatrix – 26 Assays Using PureCol Collagen)


After a long time with very limited opportunities to meet our highly valued customers in person, we are now looking forward to meeting you again.
Come by our booth at
49. ADF-Tagung, 22 – 25 February 2023, Innsbruck, Austria
3D Cell Culture 2023, 17 – 19 April 2023, Freiburg, Germany
and don’t miss out on information about new and relevant products & services for your research area of interest.

We are hoping to see you there!

Your CellSystems Team


“Giving Up is Not an Option”

On June 2, 2022, Katharina, the daughter of our scientific sales representative Monika Kleu, participated in the “Alpe d’HuZes”, a unique sporting event that raises funds for cancer research and improves the quality of life for those affected by cancer.

“Giving up is not an option” was the motto of this fundraising event and also the slogan of Katharina’s Bee Team, led by Gerdi Poelstra-Luurs. The team proved to be an exceptional “A-Team” and successfully conquered the 21 turns (15 km) through the Alps.

As a joint sponsor, CellSystems GmbH was delighted to support this initiative, contributing to the significant amount donated.

Congratulations to the Bee Team!


CellSystems mentioned in Labourjournal 1-2/2022

CellSystems offers products for enzymatic cell dissociation (Laborjournal 1-2/2022; link).


Additional enzymes for cell dissociation:




Proteinase K





TOP 5 Searches at our website


CellSystems mentioned in BIOspektrum 2021-07: 3D-Zellkultur

CellSystems offers products for 3D cell culture applications (link)