Lifeink® 200; Type I Collagen Bioink

Cat.-Nr.: 5278-5ML

Description

For printing with Lifeink® 200, we highly recommend using the FRESH printing technique and printing at 2-8°C. Three dimensional (3D) gels allow for the study of the effects of the mechanical properties of the extracellular matrix (ECM), such as density and rigidity, on cell development, migration, and morphology. Unlike 2D systems, 3D environments allow cell extensions to simultaneously interact with integrins on all cell surfaces, resulting in the activation of specific signaling pathways. Gel stiffness or rigidity also affects cell migration differently in 3D versus 2D environments.

A bioink that resembles life should include the following traits: High Print Resolution, shear-thinning, strong mechanical strength, superior cytocompatibility, allow for cellular remodeling, and is biomimetic. Lifeink® 200 fulfills those requirements.

Advanced BioMatrix offers Lifeink® 200, a bioink that is a 35 mg/ml type I collagen. Lifeink® 200 is pH neutral collagen with physiological salt concentration. The collagen starting material is purified using a controlled manufacturing process.

 

For an overview of our complete portfolio of Bioinks (click)

  • SUPPLIER:

    Advanced BioMatrix

  • STATUS:

    In Stock

  • SIZE:

    5 ml

Overview

  • Species: Bovine
  • Additional Attributes: 3D Hydrogels, Bioinks for 3D Bioprinting, collagen
  • Specific Attributes: atelocollagen/pepsin treatment, steril, Type I
  • Features:30-45 mg/ml

Related Files

Datasheet
Certificate of Origin
Declaration of Material Source

References

  • References for Lifeink® collagen bioinks:
  • Lee, A. et al. 3D bioprinting of collagen to rebuild components of the human heart. Science 365, 482–487 (2019).
  • Maxson, Eva L., et al. "In vivo remodeling of a 3D-Bioprinted tissue engineered heart valve scaffold." Bioprinting (2019): e00059.
  • Filardo, G. et al.Patient-specific meniscus prototype based on 3D bioprinting of human cell-laden scaffold. Bone & Joint Research 8,101–106 (2019).
  • Schmitt, T. Analysis and Classification of 3-D Printed Collagen-Bioglass Matrices for Cellular Growth Utilizing Artificial Neural Networks. University Thesis (2018).
  • Balakhovsky, Y. M., Ostrovskiy, A. Y. & Khesuani, Y. D. Emerging Business Models Toward Commercialization of Bioprinting Technology. 3D Printing and Biofabrication1–22 (2017). doi:10.1007/978-3-319-40498-1_25-1
  • Fox, S. et al. A simplified fabrication technique for cellularized high-collagen dermal equivalents. Biomedical Materials14,041001 (2019).

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