Worthington Biochemical Corporation
Worthington Biochemical
Worthington is a primary manufacturer of purified enzymes and biochemicals for life science research. Founded in 1947 and based in Lakewood, New Jersey, the family-owned company has spent decades refining the purification of enzymes for cell biology, tissue dissociation, molecular biology and nucleic acid research – earning its products a permanent place in methods sections around the world.
CellSystems is the official distributor of Worthington since 1992. We are listed on Worthington’s international distributor directory and supply the complete Worthington range of enzymes for tissue dissociation, primary cell isolation, molecular biology and biochemical research to universities, research institutes and industry.
All products are original Worthington material, shipped from our stock in Troisdorf, Germany. Every lot is delivered with its lot-specific certificate of analysis, and safety data sheets are available for all products.
Tissue Dissociation Enzymes
The portfolio Worthington is best known for: enzymes for isolating viable cells from virtually any tissue. From the classic Collagenases and Dispase through Papain and Trypsin to Elastase and Hyaluronidase, each enzyme is available in multiple purity grades matched to the demands of your protocol. For standardised workflows, ready-to-use Tissue Dissociation Kits combine the right activities for specific tissues. If you are choosing an enzyme or optimising a digest, our Collagenase Wiki covers types, activities and tissue-specific recommendations in depth, or take advantage of the Collagenase Sampling Program and Lot Matching Service we provide.
Molecular Biology: DNases, RNases & More
Worthington nucleases are indispensable tools of nucleic acid research. Our range covers DNase & related products – including the DNase I found in countless dissociation and single-cell workflows – alongside RNase & related products and further enzymes for molecular biology. All with the lot-level documentation you need for reproducible work.
Purified Enzymes for Biochemistry
Beyond dissociation and nucleases, Worthington manufactures a broad catalogue of purified enzymes across all major classes – hydrolases such as Chymotrypsin, Clostripain and Cellulase, oxidoreductases such as Catalase and dehydrogenases, plus esterases, lipases and more. Many products are available from as little as 10 mg up to bulk quantities, so the same well-characterised enzyme scales with your project from pilot to production.
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Chymotrypsin, 3 x cryst. - CDI
Cat.-Nr: LS001451
3X crystallized alpha chymotrypsin which is an activation product of a 3X crystallized zymogen. Dialyzed against 1mM HCl and lyophilized.
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Chymotrypsin, 3 x cryst. - CDI
Cat.-Nr: LS001450
3X crystallized alpha chymotrypsin which is an activation product of a 3X crystallized zymogen. Dialyzed against 1mM HCl and lyophilized.
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Chymotrypsin, 3 x cryst. - CDI
Cat.-Nr: LS001448
3X crystallized alpha chymotrypsin which is an activation product of a 3X crystallized zymogen. Dialyzed against 1mM HCl and lyophilized.
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Chymotrypsin, 3x cryst., TLCK treated - CDTLCK
Cat.-Nr: LS001434
3X crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219... Read More
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Chymotrypsin, 3x cryst., TLCK treated - CDTLCK
Cat.-Nr: LS001432
3X crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219... Read More
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Chymotrypsin, Alpha, 3x cryst., TLCK treated - CDTLCK
Cat.-Nr: LS001430
Chymotrypsin is a serine endopeptidase produced by the acinar cells of the pancreas. Chymotrypsin becomes activated after proteolysis of... Read More
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Chymotrypsin, Alpha, TLCK treated - CDSEQ
Cat.-Nr: LS02132
3X crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219... Read More
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Chymotrypsin, Alpha, TLCK treated - CDSEQ
Cat.-Nr: LS02130
3X crystallized and treated with 1-chloro-3-tosylamido-7-amino-2-heptanone (TLCK) to inhibit trypsin activity [Shaw, et al., Biochemistry, 4, 2219... Read More
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Chymotrypsinogen A - CGC
Cat.-Nr: LS005630
5X crystallized, electrophoretically homogeneous. Supplied as a dialyzed, lyophilized powder. Intrinsic activity ≤ 0.25 u/mg chymotrypsin.
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Chymotrypsinogen A - CGC
Cat.-Nr: LS005623
5X crystallized, electrophoretically homogeneous. Supplied as a dialyzed, lyophilized powder. Intrinsic activity ≤ 0.25 u/mg chymotrypsin.
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Clostripain - CP
Cat.-Nr: LS001646
Chromatographically purified. A dialyzed, lyophilized pre-activated powder.
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Clostripain - CP
Cat.-Nr: LS001643
Chromatographically purified. A dialyzed, lyophilized pre-activated powder.
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Clostripain - CP
Cat.-Nr: LS001641
Clostripain (Endoproteinase-Arg-C) is a two chain proteinase associated with collagenase and isolated from Clostridium histolyticum. It is highly... Read More
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Clostripain (Endoproteinase-Arg-C) Seq. - CPSEQ
Cat.-Nr: LS02135
Chromatographically purified. A dialyzed, lyophilized, pre-activated powder. Supplied in 10 ug high recovery vials. =50 units per mg dry weight
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Collagen, bovine, lyophilized - CL (10g)
Cat.-Nr: LS001656
Type I collagen prepared by the method of Einbinder and Schubert, J. Biol. Chem., 188, 335 (1951). Supplied as a shredded, lyophilized, insoluble... Read More
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Collagen, bovine, lyophilized - CL (1g)
Cat.-Nr: LS001654
Type I collagen prepared by the method of Einbinder and Schubert, J. Biol. Chem., 188, 335 (1951). Supplied as a shredded, lyophilized, insoluble... Read More
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Collagen, bovine, lyophilized - CL (5g)
Cat.-Nr: LS001652
Type I collagen prepared by the method of Einbinder and Schubert, J. Biol. Chem., 188, 335 (1951). Supplied as a shredded, lyophilized, insoluble... Read More
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Collagenase Type 1 - CLS-1 (100mg)
Cat.-Nr: LS004194
The original balance of enzymatic activities. Each lot assayed for collagenase, caseinase, clostripain and tryptic activities. Suggested for... Read More
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Collagenase Type 1 - CLS-1 (1g)
Cat.-Nr: LS004196
Worthington Collagenase Type 1 preserves the original balance of collagenase, caseinase, clostripain, and tryptic activities. This formulation is... Read More
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Collagenase Type 1 - CLS-1 (5g)
Cat.-Nr: LS004197
The original balance of enzymatic activities. Each lot assayed for collagenase, caseinase, clostripain and tryptic activities. Suggested for... Read More
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Collagenase Type 1, Filtered - CLSS-1 (1g)
Cat.-Nr: LS004217
Worthington Collagenase Type 1 preserves the original balance of collagenase, caseinase, clostripain, and tryptic activities. This formulation is... Read More
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Collagenase Type 1, Filtered - CLSS-1 (50mg)
Cat.-Nr: LS004214
Worthington Collagenase Type 1 preserves the original balance of collagenase, caseinase, clostripain, and tryptic activities. This formulation is... Read More
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Collagenase Type 1, Filtered - CLSS-1 (5x50mg)
Cat.-Nr: LS004216
Worthington Collagenase Type 1 preserves the original balance of collagenase, caseinase, clostripain, and tryptic activities. This formulation is... Read More
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Collagenase Type 2 - CLS-2 (100mg)
Cat.-Nr: LS004174
Collagenase Type II (CLS-2, Collagenase Type II) is prepared to contain a higher clostripain activity. Suggested for bone, heart, liver, thyroid and... Read More
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Collagenase Type 2 - CLS-2 (1g)
Cat.-Nr: LS004176
Worthington Collagenase Type 2 is enriched for clostripain and associated proteolytic activities, making it particularly effective for dissociating... Read More
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Collagenase Type 2 - CLS-2 (5g)
Cat.-Nr: LS004177
Prepared to contain higher clostripain activity. Suggested for bone, heart, liver, thyroid and salivary primary cell isolation. Supplied as a... Read More
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Collagenase Type 2, Filtered - CLSS-2 (1g)
Cat.-Nr: LS004205
Worthington Collagenase Type 2 is a collagenase preparation enriched for clostripain and other proteolytic activities, recommended for efficient... Read More
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Collagenase Type 2, Filtered - CLSS-2 (50mg)
Cat.-Nr: LS004202
Worthington Collagenase Type 2 is a collagenase preparation enriched for clostripain and other proteolytic activities, recommended for efficient... Read More
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Collagenase Type 2, Filtered - CLSS-2 (5x50mg)
Cat.-Nr: LS004204
Worthington Collagenase Type 2 is enriched for clostripain and associated proteolytic activities, making it particularly effective for dissociating... Read More
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Collagenase Type 3 - CLS-3 (100mg)
Cat.-Nr: LS004180
Worthington Collagenase Type 3 offers typical collagenase activity with lower levels of secondary proteases and other proteolytic contaminants. It is... Read More
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Collagenase Type 3 - CLS-3 (1g)
Cat.-Nr: LS004182
Worthington Collagenase Type 3 offers typical collagenase activity with lower levels of secondary proteases and other proteolytic contaminants. It is... Read More
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Collagenase Type 3 - CLS-3 (5g)
Cat.-Nr: LS004183
Worthington Collagenase Type 3 offers typical collagenase activity with lower levels of secondary proteases and other proteolytic contaminants. It is... Read More
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Collagenase Type 3, Filtered - CLSS-3 (50mg)
Cat.-Nr: LS004206
Worthington Collagenase Type 3 offers typical collagenase activity with lower levels of secondary proteases and other proteolytic contaminants. It is... Read More
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Collagenase Type 3, Filtered - CLSS-3 (5x50mg)
Cat.-Nr: LS004208
Worthington Collagenase Type 3 offers typical collagenase activity with lower levels of secondary proteases and other proteolytic contaminants. It is... Read More
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Collagenase Type 4 - CLS-4 (100mg)
Cat.-Nr: LS004186
Worthington Collagenase Type 4 is a low-tryptic-activity collagenase preparation designed to help minimize damage to cell-surface proteins and... Read More
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Collagenase Type 4 - CLS-4 (1g)
Cat.-Nr: LS004188
Worthington Collagenase Type 4 is a low-tryptic-activity collagenase preparation designed to help minimize damage to cell-surface proteins and... Read More
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Collagenase Type 4 - CLS-4 (5g)
Cat.-Nr: LS004189
Worthington Collagenase Type 4 is a low-tryptic-activity collagenase preparation designed to help minimize damage to cell-surface proteins and... Read More
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Collagenase Type 4, Filtered - CLSS-4 (1g)
Cat.-Nr: LS004209
Worthington Collagenase Type 4 is a low-tryptic-activity collagenase preparation designed to help minimize damage to cell-surface proteins and... Read More
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Collagenase Type 4, Filtered - CLSS-4 (50mg)
Cat.-Nr: LS004210
Worthington Collagenase Type 4 is a low-tryptic-activity collagenase preparation designed to help minimize damage to cell-surface proteins and... Read More
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Collagenase Type 4, Filtered - CLSS-4 (5x50mg)
Cat.-Nr: LS004212
Worthington Collagenase Type 4 is a low-tryptic-activity collagenase preparation designed to help minimize damage to cell-surface proteins and... Read More
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Collagenase Type 5 - CLS-5 (100mg)
Cat.-Nr: LS005280
Worthington Collagenase Type 5 contains higher collagenase and caseinase activities and is particularly suited for the dissociation of dense... Read More
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Collagenase Type 5 - CLS-5 (1g)
Cat.-Nr: LS005282
Worthington Collagenase Type 5 contains higher collagenase and caseinase activities and is particularly suited for the dissociation of dense... Read More
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Collagenase Type 5 - CLS-5 (5g)
Cat.-Nr: LS005283
Worthington Collagenase Type 5 contains higher collagenase and caseinase activities and is particularly suited for the dissociation of dense... Read More
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Collagenase Type 5, Filtered - CLSS-5 (1g)
Cat.-Nr: LS005288
Worthington Collagenase Type 5 contains higher collagenase and caseinase activities and is particularly suited for the dissociation of dense... Read More
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Collagenase Type 5, Filtered - CLSS-5 (50mg)
Cat.-Nr: LS005286
Worthington Collagenase Type 5 contains higher collagenase and caseinase activities and is particularly suited for the dissociation of dense... Read More
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Collagenase Type 5, Filtered - CLSS-5 (5x50mg)
Cat.-Nr: LS005287
Worthington Collagenase Type 5 contains higher collagenase and caseinase activities and is particularly suited for the dissociation of dense... Read More
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Collagenase Type 6 - CLS-6 (100mg)
Cat.-Nr: LS005318
Prepared to contain above normal collagenase, FALGPA and Caseinase activities and designed to be enriched with Type II (col H)... Read More
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Collagenase Type 6 - CLS-6 (2.5g)
Cat.-Nr: LS005321
Prepared to contain above normal collagenase, FALGPA and Caseinase activities and designed to be enriched with Type II (col H)... Read More
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Collagenase Type 6 - CLS-6 (500mg)
Cat.-Nr: LS005319
Worthington Collagenase Type 6 is a high-activity collagenase preparation with elevated collagenase, FALGPA and caseinase activities. It has a... Read More
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Collagenase Type 7 - CLS-7 (100mg)
Cat.-Nr: LS005332
Worthington Collagenase Type 7 contains collagenase and caseinase activities approximately four-fold higher than those of Collagenase Types 1 and 2.... Read More




