Shop Banner

Search for Product

Product categories

Search for Product

Reset

Featured Categories

  • No categories

Prolytix


Prolytix is a US protein chemistry and bioanalytical company based in Essex Junction, Vermont. Founded in 1987 as Haematologic Technologies, the company built its reputation over more than three decades on the purification and characterisation of haemostasis proteins and has since grown into a contract research partner for large-molecule biotherapeutics, offering analytical, bioanalytical and GMP testing services alongside its reagent manufacturing. The name Prolytix was adopted in March 2022, when the reagent business and Haemtech Biopharma Services were brought together under one name.

CellSystems distributes the Prolytix reagent portfolio and has been a partner since 2002, listed in the manufacturer’s distributor directory. Every shipment is accompanied by the manufacturer’s lot-specific Certificate of Analysis.

Prolytix purifies coagulation factors and related proteins directly from human and animal plasma, including prothrombin, thrombin and other vitamin K-dependent clotting factors. A particular highlight is corn trypsin inhibitor (CTI), a specific inhibitor of Factor XIIa used to block contact activation in coagulation assays and one of the few commercially available preparations of its kind. The range extends further to proteins such as osteocalcin and bovine lactadherin. Browse our Coagulation Proteins and Bone Related Proteins categories for the current selection.

Immunodepleted single-factor-deficient plasmas are a core Prolytix competence and a standard tool for clotting assays and factor activity testing. The available range is listed in our Factor Deficient Plasmas category.

Prolytix produces monoclonal and polyclonal antibodies against coagulation factors and haemostasis-related targets, raised and validated in-house against its own purified proteins. See our Coagulation Antibodies category.

For kinetic and activity assays, Prolytix offers fluorogenic substrates and inhibitors matched to its protein portfolio, listed under Fluorogenic Substrates & Inhibitors.

The SCAT blood collection tubes are one of the most distinctive parts of the Prolytix catalogue, developed for coagulation research and for sample collection within clinical studies, and built on the same expertise behind reagents such as corn trypsin inhibitor. Prolytix manufactures them to customer specification, with small batch sizes available on request, a flexibility few suppliers in this field offer. All tubes are supplied for research and development use; they are not CE-marked and are not in vitro diagnostic devices. The current formats are listed in our Sample Collection Tubes category.

Ordering Prolytix through CellSystems means original material sourced directly from the manufacturer, with EU-side import and customs handling taken care of for you, complete lot documentation, and support in English and German. Only part of the Prolytix range is listed online; the full catalogue is available on request via our contact page.

  • Human Activated Protein C-DEGR (active site blocked)

    Human Activated Protein C-DEGR (active site blocked)

    Cat.-Nr: HCAPC-DEGR

    Activated protein C (APC) is an anticoagulant serine protease derived from the two chain, vitamin K-dependent zymogen, protein C (3-7). A complex... Read More

  • Human alpha Thrombin-BFPRCK

    Human alpha Thrombin-BFPRCK

    Cat.-Nr: HCT-BFPRCK

    Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). During coagulation, thrombin... Read More

  • Human Alpha-2-Plasmin Inhibitor

    Human Alpha-2-Plasmin Inhibitor

    Cat.-Nr: HA2AP-0230

    α2 –plasmin inhibitor (α2 -PI) is a single-chain glycoprotein and is one of the major serine proteinase inhibitors circulating in plasma.... Read More

  • Human alpha-Thrombin

    Human alpha-Thrombin

    Cat.-Nr: HCT-0020

    Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). During coagulation, thrombin... Read More

  • Human alpha-Thrombin-DFP (active site blocked)

    Human alpha-Thrombin-DFP (active site blocked)

    Cat.-Nr: HCT-DFP

    Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). During coagulation, thrombin... Read More

  • Human Antithrombin III

    Human Antithrombin III

    Cat.-Nr: HCATIII-0120

    Antithrombin III (ATIII) is a single chain glycoprotein with a molecular weight of 58,000. It is a member of the serpin (serine protease inhibitor)... Read More

  • Human beta Thrombin

    Human beta Thrombin

    Cat.-Nr: HCBT-0022

    Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). Purified forms of -thrombin... Read More

  • Human beta-Factor Xa

    Human beta-Factor Xa

    Cat.-Nr: HCBXA-0061

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Beta-Thromboglobulin

    Human Beta-Thromboglobulin

    Cat.-Nr: HBTG-0210

    -thromboglobulin (-TG), is a low molecular weight, heparin-binding, platelet-derived protein (1). It is similar to platelet factor-4 (PF-4) in that... Read More

  • Human D-Dimer

    Human D-Dimer

    Cat.-Nr: HDD-0151

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Factor IX

    Human Factor IX

    Cat.-Nr: HCIX-0040

    The zymogen factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver (1-3). The domain structure of factor IX... Read More

  • Human Factor IX, biotinylated

    Human Factor IX, biotinylated

    Cat.-Nr: HCIX-0040-B

    The zymogen factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver (1-3). The domain structure of factor IX... Read More

  • Human Factor IXa

    Human Factor IXa

    Cat.-Nr: HCIXA-0050

    Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More

  • Human Factor IXa-DEGR

    Human Factor IXa-DEGR

    Cat.-Nr: HCIXA-DEGR

    Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More

  • Human Factor IXa-EGR

    Human Factor IXa-EGR

    Cat.-Nr: HCIXA-EGR

    Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More

  • Human Factor IXa, biotinylated

    Human Factor IXa, biotinylated

    Cat.-Nr: HCIXA-0050-B

    Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More

  • Human Factor V

    Human Factor V

    Cat.-Nr: HCV-0100

    Factor V is a large, single chain, plasma glycoprotein which is an essential component in the blood coagulation cascade (1). During coagulation, the... Read More

  • Human Factor Va

    Human Factor Va

    Cat.-Nr: HCVA-0110

    Factor Va is a cofactor for the serine protease factor Xa, and in the presence of calcium ions they collectively assemble on a phospholipid surface... Read More

  • Human Factor VII

    Human Factor VII

    Cat.-Nr: HCVII-0030

    Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver (1-3). Prior to secretion into the... Read More

  • Human Factor VIIa

    Human Factor VIIa

    Cat.-Nr: HCVIIA-0031

    Human factor VII is a single chain plasma glycoprotein, and is a zymogen in its native form (1-4). Proteolytic activation of factor VII, yields the... Read More

  • Human Factor X

    Human Factor X

    Cat.-Nr: HCX-0050

    Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More

  • Human Factor X, biotinylated

    Human Factor X, biotinylated

    Cat.-Nr: HCX-0050-B

    Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More

  • Human Factor Xa

    Human Factor Xa

    Cat.-Nr: HCXA-0060

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor Xa-BEGRck (active site blocked)

    Human Factor Xa-BEGRck (active site blocked)

    Cat.-Nr: HCXA-BEGR

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor Xa-DEGRck (active site blocked)

    Human Factor Xa-DEGRck (active site blocked)

    Cat.-Nr: HCXA-DEGR

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor Xa, biotinylated

    Human Factor Xa, biotinylated

    Cat.-Nr: HCXA-0060-B

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor Xa, EGRck (active site blocked)

    Human Factor Xa, EGRck (active site blocked)

    Cat.-Nr: HCXA-EGR

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor XI

    Human Factor XI

    Cat.-Nr: HCXI-0150

    Factor XI is a plasma glycoprotein which circulates in a non-covalent complex with high molecular weight kininogen (1). The mature molecule is... Read More

  • Human Factor XIa

    Human Factor XIa

    Cat.-Nr: HCXIA-0160

    Proteolysis of XI by factor XIIa in the presence of high molecular weight kininogen (HMWK), yields the enzyme factor XIa (1-3). Factor XIa is a... Read More

  • Human Factor XII

    Human Factor XII

    Cat.-Nr: HCXII-0155

    Factor XII (XII) (Hageman Factor) is a single chain (Mr=78,000) glycoprotein zymogen that circulates in plasma at a concentration of 40 µg/ml (1-5).... Read More

  • Human Factor XIII

    Human Factor XIII

    Cat.-Nr: HCXIII-0160

    Factor XIII is the zymogenic form of the glutaminyl-peptide -glutamyl transferase factor XIIIa (fibrinoligase, plasma transglutaminase, fibrin... Read More

  • Human Factor XIIIa

    Human Factor XIIIa

    Cat.-Nr: HCXIIIA-0165

    Factor XIIIa (FXIIIa) (fibrinoligase, plasma transglutaminase, fibrin stabilizing factor, E.C. 2.3.2.13) is a glutaminyl-peptide -glutamyl... Read More

  • Human Fibrinogen Fragment D

    Human Fibrinogen Fragment D

    Cat.-Nr: HCI-0150D

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Fibrinogen Fragment E

    Human Fibrinogen Fragment E

    Cat.-Nr: HCI-0150E

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Fibrinogen Research Grade

    Human Fibrinogen Research Grade

    Cat.-Nr: HCI-0150R

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Fibronectin

    Human Fibronectin

    Cat.-Nr: HCFN-0170

    Fibronectin (cold-insoluble globulin) is a high molecular weight, adhesive, glycoprotein found in both plasma (1) and the extracellular matrix (2).... Read More

  • Human gamma Thrombin

    Human gamma Thrombin

    Cat.-Nr: HCGT-0021

    Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). Purified forms of -thrombin... Read More

  • Human Gla-domainless Factor X

    Human Gla-domainless Factor X

    Cat.-Nr: HCX-GD

    Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More

  • Human gla-Domainless Factor Xa

    Human gla-Domainless Factor Xa

    Cat.-Nr: HCXA-GD

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Glu-Plasminogen

    Human Glu-Plasminogen

    Cat.-Nr: HCPG-0130

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Glu-Plasminogen (affinity form I)

    Human Glu-Plasminogen (affinity form I)

    Cat.-Nr: HCPG-0131

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Glu-Plasminogen (affinity form II)

    Human Glu-Plasminogen (affinity form II)

    Cat.-Nr: HCPG-0132

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Heparin Cofactor II

    Human Heparin Cofactor II

    Cat.-Nr: HCII-0190

    Heparin cofactor II (HCII) (heparin cofactor A, antithrombin BM, dermatan sulfate cofactor, human leuserpin-2) is a single chain glycoprotein (Mr =... Read More

  • Human Lyophilized Phospholipid Vesicles

    Human Lyophilized Phospholipid Vesicles

    Cat.-Nr: PCPS-02

    For the enzymatic reactions of the coagulation cascade to occur at physiologically relevant rates, the components must be localized to an appropriate... Read More

  • Human lys-Plasminogen

    Human lys-Plasminogen

    Cat.-Nr: HCPG-0133

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Osteocalcin

    Human Osteocalcin

    Cat.-Nr: HOC-0302

    Osteocalcin, also known as Bone-Gla-Protein (BGP), is a single chain (Mr = 5800) vitamin K dependent protein produced by osteoblasts and found in... Read More

  • Human Plasmin

    Human Plasmin

    Cat.-Nr: HCPM-0140

    Plasminogen (whether Glu-1, Lys-77 or Val-442) is converted to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond... Read More

  • Human Platelet Factor 4

    Human Platelet Factor 4

    Cat.-Nr: HPF4-0180

    Platelet factor-4 (PF-4) is a low molecular weight, heparin-binding protein which is secreted from agonist-activated platelets (1,2). PF-4 is... Read More

  • Human Platelet Osteonectin (SPARC)

    Human Platelet Osteonectin (SPARC)

    Cat.-Nr: HON-0303

    Osteonectin is an acidic, noncollagenous glycoprotein (Mr = 29,000) originally isolated from fetal and adult bovine bone matrix (1-5). In vitro... Read More

  • Human Platelet-Poor Plasma

    Human Platelet-Poor Plasma

    Cat.-Nr: HPPP-0400

    High-Quality Plateled-Poor Plasma (PPP) pooled from normal plasma for Coagulation Testing & Research Elevate your research with Prolytix... Read More