Coagulation Proteins
Coagulation Proteins for Hemostasis and Thrombosis Research
Coagulation proteins play a crucial role in maintaining hemostasis and preventing excessive bleeding. The coagulation protein products encompass a range of essential components, including coagulation enzymes, zymogens, cofactors, as well as platelet and plasma proteins from human, bovine, and murine source plasma. These native proteins are highly purified (> 95%), well-characterized and fully functional.
These products are instrumental in studying various aspects of coagulation, such as the clotting cascade, fibrinolysis, and thrombus formation. Researchers utilize these proteins to investigate the mechanisms underlying clot formation and dissolution, elucidate the pathophysiology of bleeding disorders and thrombotic diseases, and develop novel therapeutic interventions.
Don’t forget to explore our product portfolio for the Coagulation Protein Antibodies as well.
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Human Gla-domainless Factor X
Cat.-Nr: HCX-GD
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More
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Human gla-Domainless Factor Xa
Cat.-Nr: HCXA-GD
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Glu-Plasminogen
Cat.-Nr: HCPG-0130
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More
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Human Glu-Plasminogen (affinity form I)
Cat.-Nr: HCPG-0131
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More
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Human Glu-Plasminogen (affinity form II)
Cat.-Nr: HCPG-0132
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More
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Human Lyophilized Phospholipid Vesicles
Cat.-Nr: PCPS-02
For the enzymatic reactions of the coagulation cascade to occur at physiologically relevant rates, the components must be localized to an appropriate... Read More
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Human lys-Plasminogen
Cat.-Nr: HCPG-0133
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More
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Human Plasmin
Cat.-Nr: HCPM-0140
Plasminogen (whether Glu-1, Lys-77 or Val-442) is converted to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond... Read More
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Human Platelet Factor 4
Cat.-Nr: HPF4-0180
Platelet factor-4 (PF-4) is a low molecular weight, heparin-binding protein which is secreted from agonist-activated platelets (1,2). PF-4 is... Read More
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Human Platelet Osteonectin (SPARC)
Cat.-Nr: HON-0303
Osteonectin is an acidic, noncollagenous glycoprotein (Mr = 29,000) originally isolated from fetal and adult bovine bone matrix (1-5). In vitro... Read More
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Human Prethrombin-1
Cat.-Nr: HCP1-0011
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prethrombin-2
Cat.-Nr: HCP2-0011
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Protein C
Cat.-Nr: HCPC-0070
The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide... Read More
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Human Protein S
Cat.-Nr: HCPS-0090
Protein S is a single chain vitamin K-dependent protein which is thought to function in both the coagulation and complement cascades (1,2).... Read More
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Human Protein Z
Cat.-Nr: HCPZ-0220
Human protein Z (PZ) is a single chain, vitamin K-dependant plasma protein (1,2). Analogous with the majority of the coagulation proteins, protein Z... Read More
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Human Prothrombin
Cat.-Nr: HCP-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prothrombin Fragment 1
Cat.-Nr: HCP1-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prothrombin Fragment 1.2
Cat.-Nr: HCP12-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prothrombin Fragment 2
Cat.-Nr: HCP2-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Thrombospondin (TSP-1)
Cat.-Nr: HCTP-0200
Thrombospondin is a high-molecular weight, heparin-binding glycoprotein constituent of human platelets (1). Ranging from 30-50 µg per 109 platelets,... Read More
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Human Tissue Factor, Native, Placental
Cat.-Nr: HTF-0310
Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa)1. It is “sequestered” on the... Read More
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Human Tissue Factor, Recombinant, Relipidated
Cat.-Nr: RLTF-0350
Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa)1. It is “sequestered” on the... Read More
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Human Vitronectin
Cat.-Nr: HVN-0230
Vitronectin is a plasma glycoprotein that circulates in the blood at a concentration range of 200 to 400 micrograms/ml constituting 0.2 to 0.5% of... Read More
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Human von Willebrand Factor
Cat.-Nr: HCVWF-0190
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature... Read More
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Human von Willebrand Factor (Factor VIII free)
Cat.-Nr: HCVWF-0191
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature... Read More
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Mouse Factor X
Cat.-Nr: MCX-5050
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More
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Mouse Factor Xa
Cat.-Nr: MCXA-5060
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Mouse Fibrinogen
Cat.-Nr: MCI-5150
The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation... Read More
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Mouse glu-Plasminogen
Cat.-Nr: MCPG-5130
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More
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Mouse Plasmin
Cat.-Nr: MCPM-5140
Plasminogen (whether Glu-1, Lys-77 or Val-442) is converted to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond... Read More
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Mouse Prothrombin
Cat.-Nr: MCP-5010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Rabbit Thrombomodulin
Cat.-Nr: RABTM-4202
Thrombomodulin (TM) is an integral membrane glycoprotein expressed on the surface of endothelial cells. Its discovery by Esmon and Owen has focused... Read More
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Rat Factor X
Cat.-Nr: RATX-9050
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More