Search for Product

Product categories

Search for Product

Reset

Featured Categories

Coagulation Proteins


Coagulation Proteins for Hemostasis and Thrombosis Research

Coagulation proteins play a crucial role in maintaining hemostasis and preventing excessive bleeding. The coagulation protein products encompass a range of essential components, including coagulation enzymes, zymogens, cofactors, as well as platelet and plasma proteins from human, bovine, and murine source plasma. These native proteins are highly purified (> 95%), well-characterized and fully functional.

…read more

These products are instrumental in studying various aspects of coagulation, such as the clotting cascade, fibrinolysis, and thrombus formation. Researchers utilize these proteins to investigate the mechanisms underlying clot formation and dissolution, elucidate the pathophysiology of bleeding disorders and thrombotic diseases, and develop novel therapeutic interventions.

Don’t forget to explore our product portfolio for the Coagulation Protein Antibodies as well.


  • Human Factor Xa, biotinylated

    Cat.-Nr: HCXA-0060-B

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor Xa, EGRck (active site blocked)

    Cat.-Nr: HCXA-EGR

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Factor XI

    Cat.-Nr: HCXI-0150

    Factor XI is a plasma glycoprotein which circulates in a non-covalent complex with high molecular weight kininogen (1). The mature molecule is... Read More

  • Human Factor XIa

    Cat.-Nr: HCXIA-0160

    Proteolysis of XI by factor XIIa in the presence of high molecular weight kininogen (HMWK), yields the enzyme factor XIa (1-3). Factor XIa is a... Read More

  • Human Factor XII

    Cat.-Nr: HCXII-0155

    Factor XII (XII) (Hageman Factor) is a single chain (Mr=78,000) glycoprotein zymogen that circulates in plasma at a concentration of 40 µg/ml (1-5).... Read More

  • Human Factor XIII

    Cat.-Nr: HCXIII-0160

    Factor XIII is the zymogenic form of the glutaminyl-peptide -glutamyl transferase factor XIIIa (fibrinoligase, plasma transglutaminase, fibrin... Read More

  • Human Factor XIIIa

    Cat.-Nr: HCXIIIA-0165

    Factor XIIIa (FXIIIa) (fibrinoligase, plasma transglutaminase, fibrin stabilizing factor, E.C. 2.3.2.13) is a glutaminyl-peptide -glutamyl... Read More

  • Human Fibrinogen Fragment D

    Cat.-Nr: HCI-0150D

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Fibrinogen Fragment E

    Cat.-Nr: HCI-0150E

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Fibrinogen Research Grade

    Cat.-Nr: HCI-0150R

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More

  • Human Fibronectin

    Cat.-Nr: HCFN-0170

    Fibronectin (cold-insoluble globulin) is a high molecular weight, adhesive, glycoprotein found in both plasma (1) and the extracellular matrix (2).... Read More

  • Human gamma Thrombin

    Cat.-Nr: HCGT-0021

    Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). Purified forms of -thrombin... Read More

  • Human Gla-domainless Factor X

    Cat.-Nr: HCX-GD

    Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More

  • Human gla-Domainless Factor Xa

    Cat.-Nr: HCXA-GD

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Human Glu-Plasminogen

    Cat.-Nr: HCPG-0130

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Glu-Plasminogen (affinity form I)

    Cat.-Nr: HCPG-0131

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Glu-Plasminogen (affinity form II)

    Cat.-Nr: HCPG-0132

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Lyophilized Phospholipid Vesicles

    Cat.-Nr: PCPS-02

    For the enzymatic reactions of the coagulation cascade to occur at physiologically relevant rates, the components must be localized to an appropriate... Read More

  • Human lys-Plasminogen

    Cat.-Nr: HCPG-0133

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Human Plasmin

    Cat.-Nr: HCPM-0140

    Plasminogen (whether Glu-1, Lys-77 or Val-442) is converted to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond... Read More

  • Human Platelet Factor 4

    Cat.-Nr: HPF4-0180

    Platelet factor-4 (PF-4) is a low molecular weight, heparin-binding protein which is secreted from agonist-activated platelets (1,2). PF-4 is... Read More

  • Human Platelet Osteonectin (SPARC)

    Cat.-Nr: HON-0303

    Osteonectin is an acidic, noncollagenous glycoprotein (Mr = 29,000) originally isolated from fetal and adult bovine bone matrix (1-5). In vitro... Read More

  • Human Prethrombin-1

    Cat.-Nr: HCP1-0011

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Human Prethrombin-2

    Cat.-Nr: HCP2-0011

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Human Protein C

    Cat.-Nr: HCPC-0070

    The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide... Read More

  • Human Protein S

    Cat.-Nr: HCPS-0090

    Protein S is a single chain vitamin K-dependent protein which is thought to function in both the coagulation and complement cascades (1,2).... Read More

  • Human Protein Z

    Cat.-Nr: HCPZ-0220

    Human protein Z (PZ) is a single chain, vitamin K-dependant plasma protein (1,2). Analogous with the majority of the coagulation proteins, protein Z... Read More

  • Human Prothrombin

    Cat.-Nr: HCP-0010

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Human Prothrombin Fragment 1

    Cat.-Nr: HCP1-0010

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Human Prothrombin Fragment 1.2

    Cat.-Nr: HCP12-0010

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Human Prothrombin Fragment 2

    Cat.-Nr: HCP2-0010

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Human Thrombospondin (TSP-1)

    Cat.-Nr: HCTP-0200

    Thrombospondin is a high-molecular weight, heparin-binding glycoprotein constituent of human platelets (1). Ranging from 30-50 µg per 109 platelets,... Read More

  • Human Tissue Factor, Recombinant, Full-length

    Cat.-Nr: RTF-0300

    Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa) (PMID: 17556654). It is... Read More

  • Human Tissue Factor, Native, Placental

    Cat.-Nr: HTF-0310

    Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa)1. It is “sequestered” on the... Read More

  • Human Tissue Factor, Recombinant, Relipidated

    Cat.-Nr: RLTF-0350

    Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa)1. It is “sequestered” on the... Read More

  • Human Vitronectin

    Cat.-Nr: HVN-0230

    Vitronectin is a plasma glycoprotein that circulates in the blood at a concentration range of 200 to 400 micrograms/ml constituting 0.2 to 0.5% of... Read More

  • Human von Willebrand Factor

    Cat.-Nr: HCVWF-0190

    Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature... Read More

  • Human von Willebrand Factor (Factor VIII free)

    Cat.-Nr: HCVWF-0191

    Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature... Read More

  • Mouse Factor X

    Cat.-Nr: MCX-5050

    Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More

  • Mouse Factor Xa

    Cat.-Nr: MCXA-5060

    Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More

  • Mouse Fibrinogen

    Cat.-Nr: MCI-5150

    The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation... Read More

  • Mouse Plasmin

    Cat.-Nr: MCPM-5140

    Plasminogen (whether Glu-1, Lys-77 or Val-442) is converted to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond... Read More

  • Mouse Plasminogen

    Cat.-Nr: MCPG-5130

    Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More

  • Mouse Prothrombin

    Cat.-Nr: MCP-5010

    Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More

  • Rabbit Thrombomodulin

    Cat.-Nr: RABTM-4202

    Thrombomodulin (TM) is an integral membrane glycoprotein expressed on the surface of endothelial cells. Its discovery by Esmon and Owen has focused... Read More

  • Rat Factor X

    Cat.-Nr: RATX-9050

    Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More