Prolytix
About the Manufacturer
Prolytix is a US protein chemistry and bioanalytical company based in Essex Junction, Vermont. Founded in 1987 as Haematologic Technologies, the company built its reputation over more than three decades on the purification and characterisation of haemostasis proteins and has since grown into a contract research partner for large-molecule biotherapeutics, offering analytical, bioanalytical and GMP testing services alongside its reagent manufacturing. The name Prolytix was adopted in March 2022, when the reagent business and Haemtech Biopharma Services were brought together under one name.
CellSystems distributes the Prolytix reagent portfolio and has been a partner since 2002, listed in the manufacturer’s distributor directory. Every shipment is accompanied by the manufacturer’s lot-specific Certificate of Analysis.
Plasma-derived Coagulation Proteins
Prolytix purifies coagulation factors and related proteins directly from human and animal plasma, including prothrombin, thrombin and other vitamin K-dependent clotting factors. A particular highlight is corn trypsin inhibitor (CTI), a specific inhibitor of Factor XIIa used to block contact activation in coagulation assays and one of the few commercially available preparations of its kind. The range extends further to proteins such as osteocalcin and bovine lactadherin. Browse our Coagulation Proteins and Bone Related Proteins categories for the current selection.
Factor-Deficient Plasmas
Immunodepleted single-factor-deficient plasmas are a core Prolytix competence and a standard tool for clotting assays and factor activity testing. The available range is listed in our Factor Deficient Plasmas category.
Antibodies for Coagulation Research
Prolytix produces monoclonal and polyclonal antibodies against coagulation factors and haemostasis-related targets, raised and validated in-house against its own purified proteins. See our Coagulation Antibodies category.
Fluorogenic Substrates & Inhibitors
For kinetic and activity assays, Prolytix offers fluorogenic substrates and inhibitors matched to its protein portfolio, listed under Fluorogenic Substrates & Inhibitors.
Sample Collection Tubes
The SCAT blood collection tubes are one of the most distinctive parts of the Prolytix catalogue, developed for coagulation research and for sample collection within clinical studies, and built on the same expertise behind reagents such as corn trypsin inhibitor. Prolytix manufactures them to customer specification, with small batch sizes available on request, a flexibility few suppliers in this field offer. All tubes are supplied for research and development use; they are not CE-marked and are not in vitro diagnostic devices. The current formats are listed in our Sample Collection Tubes category.
Why order Prolytix through CellSystems?
Ordering Prolytix through CellSystems means original material sourced directly from the manufacturer, with EU-side import and customs handling taken care of for you, complete lot documentation, and support in English and German. Only part of the Prolytix range is listed online; the full catalogue is available on request via our contact page.
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Human Prethrombin-1
Cat.-Nr: HCP1-0011
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prethrombin-2
Cat.-Nr: HCP2-0011
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Protein C
Cat.-Nr: HCPC-0070
The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide... Read More
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Human Protein S
Cat.-Nr: HCPS-0090
Protein S is a single chain vitamin K-dependent protein which is thought to function in both the coagulation and complement cascades (1,2).... Read More
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Human Protein Z
Cat.-Nr: HCPZ-0220
Human protein Z (PZ) is a single chain, vitamin K-dependant plasma protein (1,2). Analogous with the majority of the coagulation proteins, protein Z... Read More
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Human Prothrombin
Cat.-Nr: HCP-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prothrombin Fragment 1
Cat.-Nr: HCP1-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prothrombin Fragment 1.2
Cat.-Nr: HCP12-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Prothrombin Fragment 2
Cat.-Nr: HCP2-0010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Human Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Cat.-Nr: TAFI-01
Thrombin Activatable Fibrinolysis Inhibitor (TAFI, Plasma pro-carboxypeptidase B, carboxypeptidase U) is a single chain glycoprotein zymogen (Mr =... Read More
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Human Thrombospondin (TSP-1)
Cat.-Nr: HCTP-0200
Thrombospondin is a high-molecular weight, heparin-binding glycoprotein constituent of human platelets (1). Ranging from 30-50 µg per 109 platelets,... Read More
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Human Tissue Factor, Recombinant, Full-length
Cat.-Nr: RTF-0300
Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa) (PMID: 17556654). It is... Read More
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Human Tissue Factor, Native, Placental
Cat.-Nr: HTF-0310
Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa)1. It is “sequestered” on the... Read More
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Human Tissue Factor, Recombinant, Relipidated
Cat.-Nr: RLTF-0350
Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa)1. It is “sequestered” on the... Read More
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Human Vitronectin
Cat.-Nr: HVN-0230
Vitronectin is a plasma glycoprotein that circulates in the blood at a concentration range of 200 to 400 micrograms/ml constituting 0.2 to 0.5% of... Read More
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Human von Willebrand Factor
Cat.-Nr: HCVWF-0190
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature... Read More
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Human von Willebrand Factor (Factor VIII free)
Cat.-Nr: HCVWF-0191
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation (1-8). The mature... Read More
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L-EGR-ANSNH-C3H7
Cat.-Nr: SN-45
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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MES-D-LGR-ANSN
Cat.-Nr: SN-7
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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Mouse Factor X
Cat.-Nr: MCX-5050
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More
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Mouse Factor Xa
Cat.-Nr: MCXA-5060
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Mouse Fibrinogen
Cat.-Nr: MCI-5150
The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation... Read More
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Mouse glu-Plasminogen
Cat.-Nr: MCPG-5130
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4... Read More
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Mouse Plasmin
Cat.-Nr: MCPM-5140
Plasminogen (whether Glu-1, Lys-77 or Val-442) is converted to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond... Read More
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Mouse Prothrombin
Cat.-Nr: MCP-5010
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver (1). Prior to secretion into plasma, prothrombin undergoes... Read More
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Prothrombin (Factor II ) deficient plasma
Cat.-Nr: FII-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Prothrombin (Factor II ) deficient plasma
Cat.-Nr: FII-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Rabbit Anti-Human Factor VIIa
Cat.-Nr: PAHFVIIA-RAB
Rabbit polyclonal to human coagulation factor VIIa
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Rabbit Thrombomodulin
Cat.-Nr: RABTM-4202
Thrombomodulin (TM) is an integral membrane glycoprotein expressed on the surface of endothelial cells. Its discovery by Esmon and Owen has focused... Read More
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Rat Factor X
Cat.-Nr: RATX-9050
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More
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Retham™ Cryoplatelets
Cat.-Nr: RET-PLT
Functional Human Cryopreserved Platelets for Research Applications Reliable access to functional human platelets remains a persistent challenge in... Read More
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Retham™ HIT Antibody
Cat.-Nr: RET-AHIT
Recombinant HIT Antibody Control for Antigen & Functional Assays Retham™ HIT Antibody is a recombinant monoclonal antibody engineered to mimic... Read More
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Sample Collection/Anticoagulant Tubes SCAT-1
Cat.-Nr: SCAT-I-3
Protease Inhibitor Blood Collection Tubes for Research Applications Many non-routine tests and applications which require the collection of blood... Read More
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Sample Collection/Anticoagulant Tubes SCAT-2
Cat.-Nr: SCAT-2
Protease Inhibitor Blood Collection Tubes for Research Applications Many non-routine tests and applications which require the collection of blood... Read More
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Sample Collection/Anticoagulant Tubes SCAT-875B
Cat.-Nr: SCAT-875B
Protease Inhibitor Blood Collection Tubes for Research Applications Many non-routine tests and applications which require the collection of blood... Read More
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SCAT - Custom Blood Collection Tubes
Cat.-Nr: SCAT-CBCT
Custom Blood Collection Tubes for Clinical Research Applications Many organizations have the need for sample collection tubes with custom... Read More
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Sheep anti-Human Factor IX, Affinity purified
Cat.-Nr: PAHFIX-SAP
Sheep polyclonal to human coagulation factor IX - affinity purified
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Sheep anti-Human Factor VIII
Cat.-Nr: PAHFVIII-S
Sheep polyclonal to human coagulation factor VIII. Specificity: Human Factor XIII (both A and B chain via Western blot). Does not recognize... Read More
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Sheep anti-Human Factor XI, Affinity purified
Cat.-Nr: PAHFXI-SAP
Sheep polyclonal to human coagulation factor XI - affinity purified
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