iPSC-derived Human Motor Neuron Kit

Human iPSC-Derived Motor Neurons for Neuromuscular Research and Disease Modeling

Human iPSC-derived motor neurons (iMNs) provide a physiologically relevant in vitro model for studying motor neuron function, neuromuscular biology, and neurodegenerative diseases. Generated from human induced pluripotent stem cells (iPSCs), these cells closely resemble primary spinal motor neurons and offer a standardized, renewable platform for neuroscience research.

Characterized by robust expression of ChAT (choline acetyltransferase) and Tuj1 (βIII-tubulin), iPSC-derived motor neurons are validated for functional maturation and their ability to form neuromuscular junctions (NMJs) with muscle cells. Healthy control and patient-derived iMNs enable disease modeling and investigation of disorders such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).

Human iPSC-derived motor neurons are ideally suited for neurodegenerative disease research, neuromuscular studies, neurotoxicity testing, drug screening, gene therapy research, and regenerative medicine applications.