Coagulation Proteins
Coagulation Proteins for Hemostasis and Thrombosis Research
Coagulation proteins play a crucial role in maintaining hemostasis and preventing excessive bleeding. The coagulation protein products encompass a range of essential components, including coagulation enzymes, zymogens, cofactors, as well as platelet and plasma proteins from human, bovine, and murine source plasma. These native proteins are highly purified (> 95%), well-characterized and fully functional.
These products are instrumental in studying various aspects of coagulation, such as the clotting cascade, fibrinolysis, and thrombus formation. Researchers utilize these proteins to investigate the mechanisms underlying clot formation and dissolution, elucidate the pathophysiology of bleeding disorders and thrombotic diseases, and develop novel therapeutic interventions.
Don’t forget to explore our product portfolio for the Coagulation Protein Antibodies as well.
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Human Tissue Factor, Recombinant, Full-length
Cat.-Nr: RTF-0300
Tissue factor (TF) is a transmembrane protein that functions as the high affinity receptor for factor VIIa (FVIIa) (PMID: 17556654). It is... Read More
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Beta2-Glycoprotein I
Cat.-Nr: B2GI-0001
β2-Glycoprotein I (β2I, Apolipoprotein H) is a highly glycosylated single chain protein (Mr=54,200) which is synthesized in the liver and... Read More
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Bovine Factor IXa
Cat.-Nr: BCIXA-1050
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Bovine Factor IXa-DEGR
Cat.-Nr: BCIXA-DEGR
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Bovine Factor IXa-EGR
Cat.-Nr: BCIXA-EGR
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Bovine Factor Va
Cat.-Nr: BCVA-1110
Factor Va is a cofactor for the serine protease factor Xa, and in the presence of calcium ions they collectively assemble on a phospholipid surface... Read More
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Bovine Factor Xa
Cat.-Nr: BCXA-1060
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Bovine Factor Xa-DEGR
Cat.-Nr: BCXA-DEGR
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Bovine Lactadherin
Cat.-Nr: BLAC-1200
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Lactadherin - ALEXA 555
Cat.-Nr: BLAC-ALEXA555
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Lactadherin - ALEXA 647
Cat.-Nr: BLAC-ALEXA647
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Lactadherin - FITC
Cat.-Nr: BLAC-FITC
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Echis Carinatus Prothrombin Activator
Cat.-Nr: ECVVII-2011
Snake venom proteases are useful tools for studying coagulation reactions. The venom proteases offered are highly purified, homogenous preparations... Read More
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Human Activated Protein C
Cat.-Nr: HCAPC-0080
Activated protein C (APC) is an anticoagulant serine protease derived from the two chain, vitamin K-dependent zymogen, protein C (3-7). A complex... Read More
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Human Activated Protein C-DEGR (active site blocked)
Cat.-Nr: HCAPC-DEGR
Activated protein C (APC) is an anticoagulant serine protease derived from the two chain, vitamin K-dependent zymogen, protein C (3-7). A complex... Read More
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Human alpha Thrombin-BFPRCK
Cat.-Nr: HCT-BFPRCK
Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). During coagulation, thrombin... Read More
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Human alpha-Thrombin
Cat.-Nr: HCT-0020
Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). During coagulation, thrombin... Read More
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Human alpha-Thrombin-DFP (active site blocked)
Cat.-Nr: HCT-DFP
Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). During coagulation, thrombin... Read More
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Human beta Thrombin
Cat.-Nr: HCBT-0022
Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). Purified forms of -thrombin... Read More
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Human beta-Factor Xa
Cat.-Nr: HCBXA-0061
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Beta-Thromboglobulin
Cat.-Nr: HBTG-0210
-thromboglobulin (-TG), is a low molecular weight, heparin-binding, platelet-derived protein (1). It is similar to platelet factor-4 (PF-4) in that... Read More
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Human D-Dimer
Cat.-Nr: HDD-0151
The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More
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Human Factor IX
Cat.-Nr: HCIX-0040
The zymogen factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver (1-3). The domain structure of factor IX... Read More
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Human Factor IX, biotinylated
Cat.-Nr: HCIX-0040-B
The zymogen factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver (1-3). The domain structure of factor IX... Read More
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Human Factor IXa
Cat.-Nr: HCIXA-0050
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Human Factor IXa-DEGR
Cat.-Nr: HCIXA-DEGR
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Human Factor IXa-EGR
Cat.-Nr: HCIXA-EGR
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Human Factor IXa, biotinylated
Cat.-Nr: HCIXA-0050-B
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Human Factor V
Cat.-Nr: HCV-0100
Factor V is a large, single chain, plasma glycoprotein which is an essential component in the blood coagulation cascade (1). During coagulation, the... Read More
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Human Factor Va
Cat.-Nr: HCVA-0110
Factor Va is a cofactor for the serine protease factor Xa, and in the presence of calcium ions they collectively assemble on a phospholipid surface... Read More
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Human Factor VII
Cat.-Nr: HCVII-0030
Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver (1-3). Prior to secretion into the... Read More
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Human Factor VIIa
Cat.-Nr: HCVIIA-0031
Human factor VII is a single chain plasma glycoprotein, and is a zymogen in its native form (1-4). Proteolytic activation of factor VII, yields the... Read More
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Human Factor X
Cat.-Nr: HCX-0050
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More
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Human Factor X, biotinylated
Cat.-Nr: HCX-0050-B
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a... Read More
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Human Factor Xa
Cat.-Nr: HCXA-0060
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Factor Xa-BEGRck (active site blocked)
Cat.-Nr: HCXA-BEGR
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Factor Xa-DEGRck (active site blocked)
Cat.-Nr: HCXA-DEGR
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Factor Xa, biotinylated
Cat.-Nr: HCXA-0060-B
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Factor Xa, EGRck (active site blocked)
Cat.-Nr: HCXA-EGR
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Human Factor XI
Cat.-Nr: HCXI-0150
Factor XI is a plasma glycoprotein which circulates in a non-covalent complex with high molecular weight kininogen (1). The mature molecule is... Read More
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Human Factor XIa
Cat.-Nr: HCXIA-0160
Proteolysis of XI by factor XIIa in the presence of high molecular weight kininogen (HMWK), yields the enzyme factor XIa (1-3). Factor XIa is a... Read More
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Human Factor XII
Cat.-Nr: HCXII-0155
Factor XII (XII) (Hageman Factor) is a single chain (Mr=78,000) glycoprotein zymogen that circulates in plasma at a concentration of 40 µg/ml (1-5).... Read More
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Human Factor XIII
Cat.-Nr: HCXIII-0160
Factor XIII is the zymogenic form of the glutaminyl-peptide -glutamyl transferase factor XIIIa (fibrinoligase, plasma transglutaminase, fibrin... Read More
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Human Factor XIIIa
Cat.-Nr: HCXIIIA-0165
Factor XIIIa (FXIIIa) (fibrinoligase, plasma transglutaminase, fibrin stabilizing factor, E.C. 2.3.2.13) is a glutaminyl-peptide -glutamyl... Read More
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Human Fibrinogen Fragment D
Cat.-Nr: HCI-0150D
The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More
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Human Fibrinogen Fragment E
Cat.-Nr: HCI-0150E
The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More
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Human Fibrinogen Research Grade
Cat.-Nr: HCI-0150R
The thrombin (IIa) catalyzed cleavage of soluble fibrinogen (Fbg) to form fibrin (Fbn) is the terminal proteolytic event in the coagulation cascade.... Read More
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Human Fibronectin
Cat.-Nr: HCFN-0170
Fibronectin (cold-insoluble globulin) is a high molecular weight, adhesive, glycoprotein found in both plasma (1) and the extracellular matrix (2).... Read More
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Human gamma Thrombin
Cat.-Nr: HCGT-0021
Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin (1). Purified forms of -thrombin... Read More