- Species: Human
- Specific Attributes: frozen
- iPSC: iPSC-Derived Hematopoietic Progenitor Cells
Applied StemCell has developed an efficient integration-free, small molecule-based method to
differentiate high-quality hematopoietic progenitor cells (HPC) from human iPSCs. The
differentiated HPCs recapitulate the phenotype and functional parameters of primary and in vivo HPCs.
We provide HPCs differentiated from an integration-free, control human iPSC line (ASE-9211),
reprogrammed from the fibroblasts of an African-American male donor. These high-purity (≥70%) cells express high levels of HPC biomarker, CD34.
To harness the full potential of our HPCs, we also provide optimized HPC Culture Basal Media (ASE-9718MM) that supports robust maintenance and functionality of the HPCs in culture. These iPSC-differentiated HPCs can be used as control lines to compare phenotype and functionality of patient-derived, genome edited iPSC-derived HPCs for drug screening applications.
Parental Tissue: Control human iPSC (ASE-9211); p15 Age: Neonate Gender: Male Ethnicity: African-American Tissue Source: Dermal Fibroblasts Reprogramming Method: Episomal Culture Conditions: Feeder-free
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