Services & Products
CRISPR-Cas9: Revolutionizing Gene Editing in Stem Cells
CRISPR-Cas9, discovered in 2012 by Jennifer Doudna and Emmanuelle Charpentier, is a revolutionary gene-editing tool that allows precise modification of DNA sequences in living organisms. This technology has enabled researchers to edit the genomes of iPSCs and other stem cells with unprecedented accuracy and efficiency.
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By harnessing CRISPR-Cas9, scientists can introduce or correct genetic mutations in iPSCs [knock-out (KO), knock-in (KI) or point mutation], making them valuable tools for modeling genetic diseases, studying developmental processes, and potentially developing personalized therapies. The combination of iPSCs and CRISPR technology holds great promise for advancing regenerative medicine and understanding the molecular mechanisms underlying various diseases.
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Astrocytes Differentiation Service from iPSC
Cat.-Nr: ASC-8005
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Cardiomyocytes Differentiation Service from iPSC
Cat.-Nr: ASC-8003
Applied StemCell, an expert in stem cell and somatic differentiation technologies offers a high-quality yet affordable custom service to... Read More
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CRISPR/Cas9 Conditional Knockout iPSC Service
Cat.-Nr: ASC-6013-2
Cell lines with a loss-of-function gene mutation is an invaluable tool for studying and understanding function of genes and gene products. But a... Read More
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CRISPR/Cas9 Knock-in iPSC Service
Cat.-Nr: ASC-6013-4
Applied StemCell is a leader in both CRISPR genome editing and iPSC technologies. We offer a combination CRISPR iPSC/ ES Cell Genome Editing Service... Read More
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CRISPR/Cas9 Knockout iPSC Service
Cat.-Nr: ASC-6013-1
Applied StemCell is a leader in both CRISPR genome editing and iPSC technologies. We offer a combination CRISPR iPSC/ ES Cell Genome Editing Service... Read More
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CRISPR/Cas9 Point Mutation iPSC Service
Cat.-Nr: ASC-6013-3
Point Mutation Cell Lines mimic mutations seen in clinical specimens and are important in vitro disease models to understand role of genes in... Read More
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Dopaminergic Neuron -mid Brain - Differentiation Service from iPSC
Cat.-Nr: ASC-8007M
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Dopaminergic Neuron Differentiation Service from iPSC
Cat.-Nr: ASC-8007
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Hematopoietic Progenitor Cell (HPC) Differentiation Service from iPSC
Cat.-Nr: ASC-8008
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Human ESC/iPSC Neural Crest Stem Cell Differentiation Service from iPSC
Cat.-Nr: ASC-8001C
Human ESC / iPSC Neural Crest Stem Cell Differentiation Service. We will differentiate your ESC/iPSC line into neural crest stem cells (NCSC) by... Read More
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iPSC Disease Modeling - Drug Screening
Cat.-Nr: ASC-8901
Drug discovery and development for neurological disorders has lagged far-behind therapeutics for other disease areas.
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iPSC Disease Modeling - Toxicology Testing
Cat.-Nr: ASC-8902
Traditionally, preclinical toxicology testing for small and large molecule bio-pharmaceutical compounds, chemicals for human consumption and use, and... Read More
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iPSC Generation Service (Episomal)
Cat.-Nr: ASC-6023
iPSC Generation is a complex process that reprograms adult somatic cells into a pluripotent, embryonic stem cell-like stage. This requires extensive... Read More
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iPSC Generation Service (Episomal) with Embryoid Body Formation
Cat.-Nr: ASC-6023E
iPSC Generation is a complex process that reprograms adult somatic cells into a pluripotent, embryonic stem cell-like stage. This requires extensive... Read More
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iPSC Generation Service (Episomal) with Teratoma Formation
Cat.-Nr: ASC-6023T
iPSC Generation is a complex process that reprograms adult somatic cells into a pluripotent, embryonic stem cell-like stage. This requires extensive... Read More
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iPSC Generation Service (mRNA)
Cat.-Nr: ASC-6022
iPSC Generation is a complex process that reprograms adult somatic cells into a pluripotent, embryonic stem cell-like stage. This requires extensive... Read More
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iPSC Generation Service (mRNA) with Embryoid Body Formation
Cat.-Nr: ASC-6022E
iPSC Generation is a complex process that reprograms adult somatic cells into a pluripotent, embryonic stem cell-like stage. This requires extensive... Read More
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iPSC Generation Service (mRNA) with Teratoma Formation
Cat.-Nr: ASC-6022T
iPSC Generation is a complex process that reprograms adult somatic cells into a pluripotent, embryonic stem cell-like stage. This requires extensive... Read More
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Microglia Differentiation Service from iPSC
Cat.-Nr: ASC-8009
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Motor Neurons Differentiation Service from iPSC
Cat.-Nr: ASC-8001M
Motor Neuron Differentiation Service from iPSCs. We will differentiate your iPSC line by using our proprietary induction protocol.
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Natural Killer (NK) Cell Differentiation Service from iPSC
Cat.-Nr: ASC-8018
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Neural Stem Cells (NSCs) Differentiation Service from iPSC
Cat.-Nr: ASC-8001
Neural Stem Cells Differentiation Service. We will differentiate your iPSC line into neural progenitor cells (NSCs) by using our proprietary... Read More
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Oligodendrocytes Differentiation Service from iPSC
Cat.-Nr: ASC-8004
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Retinal Pigment Epithelium (RPE) Differentiation Service from iPSC
Cat.-Nr: ASC-8010
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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Skeletal Muscle Differentiation Service from iPSC
Cat.-Nr: ASC-8013
Applied StemCell is a leader in iPSC technologies and applies established protocols for the differentiation to a specific celltype.
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TARGATT™ HEK293 Master Cell Line & Knockin Kit (Academic Price)
Cat.-Nr: AST-1305
The TARGATT™ HEK293 Master Cell Line and Knockin Kit was designed for fast and site-specific knockin in HEK293 cells, using an easy-to-use gene... Read More
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TARGATT™ Master Cell Line Generation Service (Custom)
Cat.-Nr: AST-6001
Applied Stem Cell Inc.’s proprietary TARGATT™ technology enables highly efficient site-specific gene insertion in mammalian cells and animals.
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TARGATT™ Site-specific Knock-in iPSC Service
Cat.-Nr: AST-6012T
The TARGATT™ master iPSC line contains a docking attP" site at a safe harbor genomic H11 or AAVS locus. Any genes of interest on an attB vector... Read More