Prolytix
About the Manufacturer
Prolytix is a US protein chemistry and bioanalytical company based in Essex Junction, Vermont. Founded in 1987 as Haematologic Technologies, the company built its reputation over more than three decades on the purification and characterisation of haemostasis proteins and has since grown into a contract research partner for large-molecule biotherapeutics, offering analytical, bioanalytical and GMP testing services alongside its reagent manufacturing. The name Prolytix was adopted in March 2022, when the reagent business and Haemtech Biopharma Services were brought together under one name.
CellSystems distributes the Prolytix reagent portfolio and has been a partner since 2002, listed in the manufacturer’s distributor directory. Every shipment is accompanied by the manufacturer’s lot-specific Certificate of Analysis.
Plasma-derived Coagulation Proteins
Prolytix purifies coagulation factors and related proteins directly from human and animal plasma, including prothrombin, thrombin and other vitamin K-dependent clotting factors. A particular highlight is corn trypsin inhibitor (CTI), a specific inhibitor of Factor XIIa used to block contact activation in coagulation assays and one of the few commercially available preparations of its kind. The range extends further to proteins such as osteocalcin and bovine lactadherin. Browse our Coagulation Proteins and Bone Related Proteins categories for the current selection.
Factor-Deficient Plasmas
Immunodepleted single-factor-deficient plasmas are a core Prolytix competence and a standard tool for clotting assays and factor activity testing. The available range is listed in our Factor Deficient Plasmas category.
Antibodies for Coagulation Research
Prolytix produces monoclonal and polyclonal antibodies against coagulation factors and haemostasis-related targets, raised and validated in-house against its own purified proteins. See our Coagulation Antibodies category.
Fluorogenic Substrates & Inhibitors
For kinetic and activity assays, Prolytix offers fluorogenic substrates and inhibitors matched to its protein portfolio, listed under Fluorogenic Substrates & Inhibitors.
Sample Collection Tubes
The SCAT blood collection tubes are one of the most distinctive parts of the Prolytix catalogue, developed for coagulation research and for sample collection within clinical studies, and built on the same expertise behind reagents such as corn trypsin inhibitor. Prolytix manufactures them to customer specification, with small batch sizes available on request, a flexibility few suppliers in this field offer. All tubes are supplied for research and development use; they are not CE-marked and are not in vitro diagnostic devices. The current formats are listed in our Sample Collection Tubes category.
Why order Prolytix through CellSystems?
Ordering Prolytix through CellSystems means original material sourced directly from the manufacturer, with EU-side import and customs handling taken care of for you, complete lot documentation, and support in English and German. Only part of the Prolytix range is listed online; the full catalogue is available on request via our contact page.
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BOC-L-(p-F)FPR-ANSNH
Cat.-Nr: SN-18
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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BOC-L-FPR-ANSNH
Cat.-Nr: SN-20
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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Bovine Bone Osteonectin (SPARC)
Cat.-Nr: BON-3010
Osteonectin is an acidic, noncollagenous glycoprotein (Mr = 29,000) originally isolated from fetal and adult bovine bone matrix (1-5). In vitro... Read More
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Bovine Factor IXa
Cat.-Nr: BCIXA-1050
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Bovine Factor IXa-DEGR
Cat.-Nr: BCIXA-DEGR
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Bovine Factor IXa-EGR
Cat.-Nr: BCIXA-EGR
Factor IXa is produced from its inactive precursor, factor IX, via proteolytic cleavage by factor XIa or the tissue factor/factor VIIa/phospholipid... Read More
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Bovine Factor Va
Cat.-Nr: BCVA-1110
Factor Va is a cofactor for the serine protease factor Xa, and in the presence of calcium ions they collectively assemble on a phospholipid surface... Read More
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Bovine Factor Xa
Cat.-Nr: BCXA-1060
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Bovine Factor Xa-DEGR
Cat.-Nr: BCXA-DEGR
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2).... Read More
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Bovine Lactadherin
Cat.-Nr: BLAC-1200
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Lactadherin - ALEXA 555
Cat.-Nr: BLAC-ALEXA555
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Lactadherin - ALEXA 647
Cat.-Nr: BLAC-ALEXA647
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Lactadherin - FITC
Cat.-Nr: BLAC-FITC
Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule... Read More
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Bovine Osteocalcin
Cat.-Nr: BOC-3020
Osteocalcin, also known as Bone-Gla-Protein (BGP), is a single chain (Mr = 5800) vitamin K dependent protein produced by osteoblasts and found in... Read More
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Burro anti-Human Prothrombin
Cat.-Nr: PAHFII-BU
Sheep polyclonal to human coagulation protein prothrombin.
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Corn Trypsin Inhibitor
Cat.-Nr: CTI-01
Corn trypsin inhibitor (CTI) is a small protein that is localized in the kernels of most species of corn. CTI is not only an inhibitor of trypsin,... Read More
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CTI Vacuum Collection Tubes SCAT Type 27
Cat.-Nr: SCAT-27-4.5/5
Purified CTI Corn trypsin inhibitor (CTI) is a small protein that is localized in the kernels of most species of corn. CTI is not only an... Read More
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D-AFK-ANSNH
Cat.-Nr: SN-5
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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D-FPR-ANSNH-C4H9(2HCl)
Cat.-Nr: SN-17c
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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D-FPR-ANSNH-C6H11X(2HCI)
Cat.-Nr: SN-17a
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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D-LPR-ANSNH-C3H7
Cat.-Nr: SN-13a
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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D-VPR-ANSNH
Cat.-Nr: SN-59
Substrates containing the fluorescent reporter group 6-amino-1-naphthalene-sulfonamide (ANSN) are useful compounds for monitoring the enzyme activity... Read More
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Dansylarginine-N-(3-ethyl-1,5-pentanediyl)amide (DAPA)
Cat.-Nr: DAPA
Dansylarginine N-(3-ethyl-1,5-pentanediyl)amide, more commonly referred to as DAPA, is a potent (Ki=10-7M) and specific synthetic inhibitor of... Read More
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Echis Carinatus Prothrombin Activator
Cat.-Nr: ECVVII-2011
Snake venom proteases are useful tools for studying coagulation reactions. The venom proteases offered are highly purified, homogenous preparations... Read More
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EGR-chloromethylketone (GGACK)
Cat.-Nr: EGRCK-01
Tri-peptide chloromethylketones have been utilized extensively to irreversibly inhibit various serine proteases (1-5). Among the most common... Read More
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Factor IX deficient plasma
Cat.-Nr: FIX-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor IX deficient plasma
Cat.-Nr: FIX-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor V deficient plasma
Cat.-Nr: FV-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor V deficient plasma
Cat.-Nr: FV-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor VII deficient plasma
Cat.-Nr: FVII-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor VII deficient plasma
Cat.-Nr: FVII-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor VIII deficient plasma
Cat.-Nr: FVIII-CD-250
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor VIII deficient plasma
Cat.-Nr: FVIII-CD-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor VIII deficient plasma
Cat.-Nr: FVIII-CD-500
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor VIII deficient plasma
Cat.-Nr: FVIII-CD-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor X deficient plasma
Cat.-Nr: FX-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor X deficient plasma
Cat.-Nr: FX-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor XI deficient plasma
Cat.-Nr: FXI-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor XI deficient plasma
Cat.-Nr: FXI-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor XII deficient plasma
Cat.-Nr: FXII-ID-1
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Factor XII deficient plasma
Cat.-Nr: FXII-ID-50
Haematologic Technologies factor deficient plasmas are for RESEARCH USE ONLY or for further manufacture into in vitro diagnostic reagents. Our... Read More
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Fluorescein EGR-chloromethylketone
Cat.-Nr: FEGRCK-06
Tri-peptide chloromethylketones have been utilized extensively to irreversibly inhibit various serine proteases (1-5). Among the most common... Read More
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Fluorescein FPR-chloromethylketone
Cat.-Nr: FFPRCK-06
Tri-peptide chloromethylketones have been utilized extensively to irreversibly inhibit various serine proteases (1-5). Among the most common... Read More
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FPR-chloromethylketone (PPACK)
Cat.-Nr: FPRCK-01
Tri-peptide chloromethylketones have been utilized extensively to irreversibly inhibit various serine proteases (1-5). Among the most common... Read More
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Human Activated Protein C
Cat.-Nr: HCAPC-0080
Activated protein C (APC) is an anticoagulant serine protease derived from the two chain, vitamin K-dependent zymogen, protein C (3-7). A complex... Read More