PhotoCol®, Methacrylated Collagen (Collagen only)

Cat.-Nr.: 5198-100MG

Description

PhotoCol® kits consists of purified methacrylated Type I bovine collagen as the core component with other support reagents in the kit. This PhotoCol® product only contains the methacrylated collagen. For the entire photocrosslinking kit, please visit any of the PhotoCol® Kit pages.

The methacrylated Type I collagen is produced from telo-peptide intact bovine collagen where the collagen has been modified by reacting the free amines, primarily the e-amines groups of the lysine residues as well as the a-amines groups on the N-termini. > 20% of the total lysine residues of the collagen molecule have been methacrylated. The collagen is extracted from bovine hide and contains a high monomer content.

 

For an overview of our tunable 3D Hydrogels (photo-crosslinking) (click)

For an overview of our tunable 3D Hydrogels (chemical-crosslinking; click)

  • SUPPLIER:

    Advanced BioMatrix

  • STATUS:

    In Stock

  • SIZE:

    100 mg

Overview

  • Species: Bovine
  • Keywords: 3D Hydrogels, Bioinks for 3D Bioprinting, Collagen, Tunable Stiffness Hydrogels
  • Specific Attributes: methacrylated, sterile, Telocollagen/acidic treatment, Type I
  • Product Type: Telocollagen
  • Features: methacrylated

Related Files

Datasheet
Certificate of Origin
Declaration of Material Source

References

  • Maloney, E. et al. Immersion Bioprinting of Tumor Organoids in Multi-Well Plates for Increasing Chemotherapy Screening Throughput. Micromachines 11, 208 (2020).
  • Isaacson, A., Swioklo, S. & Connon, C. J. 3D bioprinting of a corneal stroma equivalent. Experimental Eye Research 173, 188–193 (2018).
  • Kathryn E. Drzewiecki et al, A thermoreversible, photocrosslinkable collagen bio-ink for free-form fabrication of scaffolds for regenerative medicine, TECHNOLOGY (2017).
  • Drzewiecki, K. E. et al. Methacrylation Induces Rapid, Temperature-Dependent, Reversible Self-Assembly of Type-I Collagen. Langmuir 30, 11204–11211 (2014).
  • Gaudet, I. D. & Shreiber, D. I. Characterization of Methacrylated Type-I Collagen as a Dynamic, Photoactive Hydrogel. Biointerphases 7, 25 (2012).
  • Izadifar, Mohammad, et al. "UV-assisted 3D bioprinting of nanoreinforced hybrid cardiac patch for myocardial tissue engineering." Tissue Engineering Part C: Methods 24.2 (2018): 74-88.
  • Stoecklin, Celine, et al. "A New Approach to Design Artificial 3D Microniches with Combined Chemical, Topographical, and Rheological Cues." Advanced Biosystems (2018): 1700237.
  • Mazzocchi, Andrea, et al. "Optimization of collagen type I-hyaluronan hybrid bioink for 3D bioprinted liver microenvironments." Biofabrication (2018).
  • Nguyen, T. U., Watkins, K. E. & Kishore, V. Photochemically crosslinked cell‐laden methacrylated collagen hydrogels with high cell viability and functionality. Journal of Biomedical Materials Research Part A107,1541–1550 (2019).
  • Mazzocchi, A. et al.Pleural Effusion Aspirate for Use in 3D Lung Cancer Modeling and Chemotherapy Screening. ACS Biomaterials Science & Engineering5,1937–1943 (2019).
  • Chhetri, A. et al. Cell Culture and Coculture for Oncological Research in Appropriate Microenvironments. Current Protocols in Chemical Biology11,(2019).

RELATED PRODUCTS


Collagen Hybridizing Peptides – CY3 ConjugatePhotoHA®, Methacrylated Hyaluronic Acid (HA Only)