Overview
- Species: Human
- Additional Attributes: Extracellular Matrix
- Specific Attributes: steril
Human Fibronectin, lyoph.
Cat.-Nr.: 5080-5MG
Description
Fibronectin is a widely used broad range natural cell attachment factor. This product has been purified from human plasma where it is found as a dimer and has a size of 440-500 kDa with two similar subunits (220-250 kDa ) linked by two disulfide bonds.
Fibronectin’s primary function is related to cell adhesion and attachment to extracellular matrix. Certain domains of Fibronectin have been found to play important roles that involve interactions with collagen, heparin and other cell surface glycosaminoglycans (GAGs).
Fibronectin is ideal for coating of surfaces and is typically used at a concentration of 1-5 µg/cm2 . It is provided in user-friendly packaging for use and storage. Fibronectin is sterile filtered and is supplied as a sterile, lyophilized product.
SUPPLIER:
Advanced BioMatrix
STATUS:
In Stock
SIZE:
5 mg
References
- Alhussein, Ghada, et al. "A spatiotemporal characterization method for the dynamic cytoskeleton." Cytoskeleton 73.5 (2016): 221-232.
- Pezzoli, Daniele, et al. "Fibronectin promotes elastin deposition, elasticity and mechanical strength in cellularised collagen-based scaffolds." Biomaterials 180 (2018): 130-142.
- Wiley, Luke A., et al. "Generation of xeno‐free, cGMP‐compliant patient‐specific iPSCs from skin biopsy." Current protocols in stem cell biology 42.1 (2017): 4A-12.
- Wiley, Luke A., et al. "Using patient-specific induced pluripotent stem cells and wild-type mice to develop a gene augmentation-based strategy to treat CLN3-associated retinal degeneration." Human gene therapy 27.10 (2016): 835-846.
- Worthington, Kristan S., et al. "Two-photon polymerization for production of human iPSC-derived retinal cell grafts." Acta biomaterialia 55 (2017): 385-395.
- Li, Ling, Mizuho Fukunaga-Kalabis, and Meenhard Herlyn. "Isolation and cultivation of dermal stem cells that differentiate into functional epidermal melanocytes." Human Cell Culture Protocols. Humana Press, 2012. 15-29.
- Boularaoui, Selwa Mokhtar, et al. "Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle." Journal of tissue engineering and regenerative medicine 12.2 (2018): e918-e936.
Human Fibronectin, Solution