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Home |Products|Cytokines and Chemokines|CTLA 4 Human

CTLA 4 Human

Cat.-Nr.: CS-C1017

Description

Cytotoxic T-Lymphocyte Associated Antigen-4 Human Recombinant produced in insect cells is a homodimeric, glycosylated, polypeptide chain containing a total molecular mass of 80 kDa. Each subunit (40kDa) is fused to a polypeptide linker to the Fc portion of Human IgG1. CTLA4 is expressed in low copy number by T-cells only after activation, but it binds CD28-ligand with approximately 20-fold higher affinity than CD28. A soluble form of the extracellular domain of CTLA-4 has been shown to bind CD28-ligand with high avidity and to suppress T-cell-dependent antibody responses in vivo. Large doses of this soluble protein also suppress responses to a second immunization. CTLA-4 is purified by proprietary chromatographic techniques.

For other quantities and bulk, please contact us.

  • SUPPLIER:

    CellSystems

  • STATUS:

    In Stock

  • SIZE:

    25 µg

  • Overview

Overview

  • Additional Attributes: Cytokines
  • Specific Attributes: Other Cytokines
  • Donor / Source:Sf9 cells.
  • Formulation:CTLA-4 was lyophilized with no additives.
  • Purity:Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
  • Amino acid sequence:The sequence of the amino acids was determined and was found to be: Lys-Ala-Met-His-Val.

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FGF 1 Human, Sf9 IL 2 Mouse
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