Leptin tA Mouse

Cat.-Nr.: CS-C2034

GM-CSF huamn

Description

Leptin Antagonist Triple Mutant Mouse Recombinant is a single non-glycosilated polypeptide chain containing 146 amino and additional Ala at N-terminus acids and having a molecular mass of ~ 16 kDa, LEP was mutated, resulting in L39A/D40A/F41A mutant. Leptin Antagonist Triple Mutant Mouse Recombinant was purified by proprietary chromatographic techniques.

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  • SUPPLIER:

    CellSystems

  • STATUS:

    In Stock

  • SIZE:

    100 µg

Overview

  • Species: Mouse
  • Keywords: Growth Factors
  • Product Type: Leptin
  • Donor / Source:Escherichia coli.
  • Formulation:The protein was lyophilized from a concentrated (0.65mg/ml) solution with 0.003mM NaHCO3.
  • Purity:Greater than 99.0% as determined by:(a) Gel filtration analysis.(b) Analysis by SDS-PAGE.
  • Amino acid sequence:The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Gln Biological ActivityProSpec’s Leptin Antagonist Triple Mutant Mouse Recombinant is capable of inhibiting Leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human Leptin receptor. It also inhibits various Leptin effects in several in vitro bioassays.

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