Fluorogenic Substrates & Inhibitors

Inhibitors are compounds that block the activity of specific enzymes or proteins involved in coagulation. In haemostasis research, inhibitors are often used to study the effects of blocking certain steps in the coagulation cascade. For example, inhibitors of Thrombin or Factor Xa can be used to investigate their roles in clot formation and stability.

Explore a wide range of inhibitors, from human protease inhibitors like Angiostatin and Thrombin Activatable Fibrinolysis Inhibitor (TAFI) to various Chloromethylketones. Furthermore, you can choose from Corn Trypsin Inhibitor (CTI) and the synthetic Thrombin inhibitor Dansylarginine N-(3-ethyl-1,5-pentanediyl)amide (DAPA) for your research needs.

Notably, CTI is available pre-aliquoted in our blood collection tubes, specifically our SCAT-27 line. These CTI Vacuum Collection Tubes (SCAT-Type 27) are for research use only and streamline Tissue Factor-dependent studies by enabling direct blood collection onto an anticoagulant (Sodium Citrate) containing CTI.

Fluorogenic substrates and inhibitors provide valuable tools monitoring haemostasis and thrombosis, as well as for developing novel diagnostic and therapeutic strategies for related disorders.