NEW! Bio-Spun™ Scaffolds for 3D Cell Culture Applications

With Bio-Spun™ Scaffolds from BioSurfaces, CellSystems now offers an innovative solution for optimising and standardising complex 3D cell cultures. Produced using a patented electrospinning technology, these scaffolds form a random, nanofibrous 3D structure that closely resembles the extracellular matrix (ECM) of natural tissue.

Comparison of an microscopic picuture of Bio-Spun scaffold material with body's natural scaffold.

Fully animal-free and available in biodegradable or non-biodegradable polymers, the scaffolds promote more physiological cell interactions, help reduce stress responses, and improve the transferability of results to in vivo systems. They also prevent unwanted ECM breakdown and remodelling – a clear advantage over many animal-derived matrices.

Typical applications include:
• Skin models (e.g. irritation, sensitisation, wound healing)
• Airway models (e.g. infection research, inhalation toxicology, drug delivery)
• Models for eye, tumour, skeletal muscle, neurons, blood-brain barrier, liver and more

Key product benefits:
• 100% animal-free
• Choice of biodegradable or non-biodegradable polymers
• Low batch-to-batch variation for reliable, reproducible results

• Saves time and cost in development and testing

Available formats:

Inserts compatible with 6-, 12- and 24-well Transwell Plates, as well as ready-to-use 24- and 96-well High-Throughput Screening Plates

• Materials:
– Non-degradable polymers (PET, PU)
– Biodegradable polymers (PDLGA, PDLGA/PLLA Bilayer)
• Membrane thicknesses:
– PET: 150 μm
– PU: 20 μm
– PDLGA: 10 μm
– PDLGA/PLLA Bilayer: 100 μm

Not sure which scaffold to choose? The Bio-Spun™ Scaffold Overview helps you match the right product to your specific application and tissue model.