Columnar Pore Architecture, 4 mm Diamater, Discs

Cat.-Nr.: 5135-25EA

Description

SpongeCol® is a collagen sponge with an interpenetrating, columnar porous architecture structure. SpongeCol® contains unique columnar porous network which permits cells and nutrients to flow completely through the interpenetrating pores and provides an increased surface area for cell attachment, growth and migration.

SpongeCol® is composed of highly purified Type I collagen which best supports the attachment, proliferation, and function of cells. The collagen is lightly cross-linked for increased mechanical strength and durability for short and long term tissue culture yet is still biodegradable over the longer-term. The diameter of the pores ranges from 100 to 400 micron with the average diameter being approximately 200 microns. The collagen disc is approximately 4 mm or 21 mm in diameter and 1.5 mm thick. The sponge discs fits into a 96-well (4 mm disc) culture plate or sanitary luer connectors for flow perfusion. Each package contains 25 (4 mm) collagen sponge discs.

This product is terminally sterilized and ready-to-use.

  • SUPPLIER:

    Advanced BioMatrix

  • STATUS:

    In Stock

  • SIZE:

    25 pcs

Overview

  • Species: Bovine
  • Keywords: 3D Hydrogels, Collagen
  • Specific Attributes: Atelocollagen/pepsin treatment, sterile, Type I
  • Product Type: Telocollagen, Type 1 / I
  • Packaging:4 mm Diamater

Related Files

Datasheet
Certificate of Origin

References

  • Mak, W. C., et al. “Thermo-Rheological Responsive Microcapsules for Time-Dependent Controlled Release of Human Mesenchymal Stromal Cells.” Biomater. Sci., vol. 5, no. 11, 2017, pp. 2241–2250., doi:10.1039/c7bm00663b.
  • Udhayakumar, Sivalingam, et al. “l-Arginine Intercedes Bio-Crosslinking of a Collagen–Chitosan 3D-Hybrid Scaffold for Tissue Engineering and Regeneration: in Silico, in Vitro, and in Vivo Studies.” RSC Advances, vol. 7, no. 40, 2017, pp. 25070–25088., doi:10.1039/c7ra02842c.
  • Ferreira, L.p., et al. “Design of Spherically Structured 3D in Vitro Tumor Models -Advances and Prospects.” Acta Biomaterialia, 2018, doi:10.1016/j.actbio.2018.05.034.
  • Hatsell, Sarah J., et al. “ACVR1 R206H Receptor Mutation Causes Fibrodysplasia Ossificans Progressiva by Imparting Responsiveness to Activin A.” Science Translational Medicine, vol. 7, no. 303, Feb. 2015, doi:10.1126/scitranslmed.aac4358.
  • Anton-Sales, I., Beekmann, U., Laromaine, A., Roig, A. & Kralisch, D. Opportunities of Bacterial Cellulose to Treat Epithelial Tissues. Current Drug Targets20,808–822 (2019).

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