iPSC-derived Photoreceptor kit

Description

The iPSC-derived Photoreceptor Kit is developed using an efficient, integration-free method to differentiate high-quality photoreceptor cells from human iPSCs. The differentiated photoreceptor cells recapitulate the phenotype and functional parameters of primary and in vivo photoreceptor cells. We provide photoreceptor cells differentiated from an integration-free, control human iPSC line (ASE-9211), reprogrammed from fibroblasts of an African-American male donor. These cryopreserved, high-purity (≥90%) cells express high levels of photoreceptor cell biomarkers, CRX and NR2E3, as well as Tuj1, Rhodopsin, and PDE6a. Please refer to the datasheet for more information.
To harness the full potential of our photoreceptor cells, we also provide optimized Photoreceptor Maturation Basal Media (ASE-9715MM) and Photoreceptor Culture Maturation Media Supplement (100x) (ASE-9715-A) that support the robust maintenance and functionality of the photoreceptor cells in culture.
These iPSC-differentiated photoreceptor cells can be used as control lines to compare phenotype and functionality of patient-derived, genome edited iPSC-derived photoreceptor cells for drug screening applications.
Parental Tissue: Control human iPSC (ASE-9211); p15
Age: Neonate
Gender: Male
Ethnicity: African-American
Tissue Source: Dermal Fibroblasts
Reprogramming Method: Episomal
Culture Conditions: Feeder-free
Clinical information: Healthy (with no known disease phenotypes)

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• SUPPLIER:

  Applied StemCell

• STATUS:

  In Stock

• SIZE:

  kit