iPSC Lines

Induced Pluripotent Stem Cells for Advanced Research
Shinya Yamanaka’s groundbreaking work on induced pluripotent stem cells (iPSCs) involved identifying a specific set of genes that could reprogram adult cells back into a pluripotent state.
Applied StemCell offers well-characterized, normal human induced pluripotent stem cells (iPSC) that have been reprogrammed from healthy human tissues (e.g., cord blood, fibroblasts, PBMCs) using footprint-free methods and Yamanaka factors. All iPSC lines have been carefully selected for morphology of undifferentiated cells, expression of pluripotency markers (OCT4, SOX2, SSEA4, and others), and strong endogenous alkaline phosphatase activity. Our normal human iPSCs have proven genome editing and differentiation capabilities, and are ideal for disease modeling, drug discovery/screening, and neurotoxicity screening applications.