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Home |Products|COVID-19 / SARS-CoV-2|Coronavirus 2019 Spike E-Mosaic Recombinant

Coronavirus 2019 Spike E-Mosaic Recombinant

Cat.-Nr.: CS-C9025

Description

A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.
The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.
While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
The E.Coli derived recombinant protein contains the Coronavirus 2019 spike Envelope Mosaic immunodominant regions having a Mwq of 40.5 kDa, fused to 6xHis tag at C-terminal.

  • SUPPLIER:

    CellSystems

  • STATUS:

    In Stock

  • SIZE:

    50 µg

  • Overview

Overview

  • Packaging:other package sizes available on request
  • Donor / Source:Escherichia Coli
  • Formulation:CoV 2019 Spike E-Mosaic Protein 1mg/ml solution is supplied in 1x PBS.
  • Amino acid sequence:S-part (20-210 a.a.)

    RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHAIHV SGTNGTKRFD NPVLPFNDGV YFASTEKSNI IRGWIFGTTL DSKTQSLLIV NNATNVVIKV CEFQFCNDPF LGVYYHKNNK SWMESEFRVY SSANNCTFEY VSQPFLMDLE GKQGNFKNLR EFVFKNIDGY FKIYSKHTPI



    E-part (51-75 a.a.)

    AYCCNIVNVS LVKPSFYVYS RVKNLNSSRV PDLLV



    M part (100-222 a.a.)

    RLFARTRSMW SFNPETNILL NVPLHGTILT RPLLESELVI GAVILRGHLR IAGHHLGRCD
    IKDLPKEITV ATSRTLSYYK LGASQRVAGD SGFAAYSRYR IGNYKLNTDH SSSSDNIALL VQ

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Coronavirus 2019 Spike (800-1000 a.a.) Recombinant Coronavirus 2019 Spike Glycoprotein-S1 Receptor Binding Domain (319-541 a.a),...
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