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Home |Products|COVID-19 / SARS-CoV-2|Coronavirus 2019 Spike (1-1211 a.a.), Recombinant

Coronavirus 2019 Spike (1-1211 a.a.), Recombinant

Cat.-Nr.: CS-C9032

Description

A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.
The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.
While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
The CHO derived recombinant protein contains the Coronavirus 2019-Spike Full-Length protein, Wuhan-Hu-1 strain, amino acids 1-1211 having a Mw of 134 kDa fused to His tag at C-terminal. The furin cleavage site (682- 685 a.a.) has been mutated from RRAR to SRAS and the transmembrane domain & intravirion part was replaced with a glycine-serine linker + His-tag

  • SUPPLIER:

    CellSystems

  • STATUS:

    In Stock

  • SIZE:

    50 µg

  • Overview

Overview

  • Packaging:other package sizes available on request
  • Donor / Source:CHO cells
  • Formulation:CoV-2 spike full length protein solution is supplied in DPBS.

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Coronavirus 2019 Spike Glycoprotein-S1 Receptor Binding Domain (319-541 a.a),... SARS-Associated Coronavirus Nucleocapsid Core Recombinant, (340-390 a.a)
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